Optimisation of HPMC ophthalmic inserts with sustained release properties as a carrier for thermolabile therapeutics
نویسندگان
چکیده
منابع مشابه
Evaluation of a newly developed HPMC ophthalmic insert with sustained release properties as a carrier for thermolabile therapeutics.
A novel drug delivery system (DDS) with sustained release properties was developed to allow ocular protein delivery. The DDS developed is aimed at overcoming stability issues during preparation such as denaturation of proteins caused by shear forces applied or due to elevated temperatures and air entrapment potentially causing oxidation of the molecule. The rod-shaped HPMC inserts were loaded w...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutics
سال: 2017
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2017.06.047